翻訳と辞書 Words near each other ・ Mir yeshiva (Jerusalem) ・ Mir Yousuf Ali Khan, Salar Jung III ・ Mir Yusof ・ Mir Yusof-e Olya ・ Mir Yusof-e Sofla ・ Mir Zafar Ali ・ Mir, Belarus ・ Mir, Iran ・ Mir-1 ・ Mir-1 microRNA precursor family ・ Mir-10 microRNA precursor family ・ Mir-101 microRNA precursor family ・ Mir-103/107 microRNA precursor ・ Mir-11 microRNA precursor family ・ MiR-122 ・ Mir-124 microRNA precursor family ・ Mir-126 ・ Mir-127 ・ Mir-129 microRNA precursor family ・ Mir-130 microRNA precursor family ・ MiR-132 ・ Mir-133 microRNA precursor family ・ MiR-134 ・ Mir-135 microRNA precursor family ・ Mir-137 ・ MiR-138 ・ Mir-14 microRNA precursor family ・ Mir-143 ・ MiR-144 ・ Mir-145 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Mir-124 microRNA precursor family ： ウィキペディア英語版 Mir-124 microRNA precursor family The miR-124 microRNA precursor is a small non-coding RNA molecule that has been identified in flies ((MI0000373 )), nematode worms ((MI0000302 )), mouse ((MI0000150 )) and human ((MI0000443 )). The mature ~21 nucleotide microRNAs are processed from hairpin precursor sequences by the Dicer enzyme, and in this case originates from the 3' arm. miR-124 has been found to be the most abundant microRNA expressed in neuronal cells. Experiments to alter expression of miR-124 in neural cells did not appear to affect differentiation. However these results are controversial since other reports have described a role for miR-124 during neuronal differentiation. ==Targets of miR-124== * Visvanathan ''et al.''. showed that miR-124 targets the mRNA of the anti-neural function protein SCP1 (small C-terminal domain phosphatase 1). * Makeyev et al. showed that miR-124 directly targets PTBP1 (PTB/hnRNP I) mRNA, which encodes a global repressor of alternative pre-mRNA splicing in non-neuronal cells. *Arrant et al. wrote that miR-124 changes glutamate receptor composition in the prefrontal cortex and can decrease social dysfunction in frontotemporal dementia. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Mir-124 microRNA precursor family」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.